Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862133 | 0.93 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8862135 | 0.92 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8862050 | 0.92 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8075117 | 0.92 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8080163 | 0.91 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8079037 | 0.90 | LTB4R (0.85) | LTB4R | |
| SCHEMBL8079040 | 0.90 | LTB4R (0.85) | LTB4R | |
| SCHEMBL8078852 | 0.90 | LTB4R (0.98) | LTB4R | |
| SCHEMBL8862103 | 0.90 | LTB4R (1.00) | LTB4R | |
| SCHEMBL1893839 | 0.89 | LTB4R (1.00) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812194-B1 | Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis | SMITHKLINE BEECHAM CORP (US) | 2000-08-16 | — | — | EP | claimed |
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | claimed |
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |