Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173907 | 0.82 | TSHR (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL639072 | 0.82 | ALDH1A1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4262832 | 0.82 | TSHR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30960327 | 0.82 | TSHR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10883241 | 0.81 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27777851 | 0.81 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31083244 | 0.81 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1097855 | 0.80 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4209895 | 0.79 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27786812 | 0.79 | CA12 (0.59) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749451-B1 | FLAME RETARDANT POLYESTER COPOLYMERS | SOLUTIA INC (US) | 2000-08-02 | — | — | EP | disclosed |
| US-5703134-A | HEATING POLYETHYLENE TEREPHTHALIC WITH DICARBOXYLIC ACID | MONSANTO COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5399428-A | Polyethylene terephthalate with hydroxyalkyl dicarboxylate and carboxy phosphinic acid | MONSANTO COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5399429-A | Dihydroxyalkyl dicarboxylates and fireproofing carboxyalkyl or aryl phosphinic acid | MONSANTO COMPANY (US) | 1995-03-21 | — | — | US | disclosed |