Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075602 | 0.88 | ALDH1A1 (0.43) | MAPK1ALDH1A1CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL8075762 | 0.81 | ACE (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL8078994 | 0.77 | MCL1 (0.44) | ALDH1A1CYP2C19SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8074931 | 0.76 | KDM4E (0.42) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL28800589 | 0.76 | KDM4E (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL120067 | 0.76 | — | — | |
| SCHEMBL8508454 | 0.76 | KDM4E (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL110457 | 0.76 | — | — | |
| SCHEMBL120068 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL100539 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |