Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075453 | 1.00 | CA2 (0.51) | CA2CA1KMT2ATRPA1TP53 | |
| SCHEMBL3339435 | 0.84 | CYP1A1 (0.53) | KMT2ATP53RAB9AALDH1A1KDM4E | |
| SCHEMBL3339432 | 0.84 | CYP1A1 (0.53) | KMT2ATP53RAB9AALDH1A1KDM4E | |
| SCHEMBL11584033 | 0.84 | KMT2A (0.46) | CA2CA1KMT2ATSHRRAB9A | |
| SCHEMBL11584029 | 0.84 | KMT2A (0.46) | CA2CA1KMT2ATSHRRAB9A | |
| SCHEMBL11587088 | 0.81 | CA1 (0.56) | CA2CA1KMT2ACA12CA9 | |
| SCHEMBL11587084 | 0.81 | CA1 (0.56) | CA2CA1KMT2ACA12CA9 | |
| Hydrochloric Acid SCHEMBL7563152 | 0.78 | TP53 (0.44) | CA2CA1KMT2ATP53TSHR | |
| Hydrochloric Acid SCHEMBL7563182 | 0.78 | TP53 (0.44) | CA2CA1KMT2ATP53TSHR | |
| Hydrochloric Acid SCHEMBL7563142 | 0.78 | TP53 (0.44) | CA2CA1KMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640591-B1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL IND (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5523027-A | AZOMETHINE COMPOUNDS; LIGHT RESISTANCE | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0640591-A1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4085062-A | ULTRAVIOLET ABSORBERS | GIVAUDAN CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |