Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899670 | 0.87 | MAPT (0.54) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9899672 | 0.87 | MAPT (0.54) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8075644 | 0.84 | ADORA2A (0.43) | CYP1A2ADORA2AADORA1 | |
| SCHEMBL18110569 | 0.75 | CHRNB4 (0.42) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18110567 | 0.75 | CHRNB4 (0.42) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9899723 | 0.71 | MAPT (0.57) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9899724 | 0.71 | MAPT (0.57) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8071105 | 0.71 | MAPT (0.68) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9900059 | 0.71 | MAPT (0.54) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2935652 | 0.70 | CHRNB4 (0.43) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |