Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060900 | 0.85 | HPGD (0.40) | HTTHPGDNPC1CYP1A2CYP2C19 | |
| SCHEMBL7245714 | 0.83 | ALDH1A1 (0.44) | SMN1; SMN2HTTLMNAHPGDNPC1 | |
| SCHEMBL8075519 | 0.83 | NPC1 (0.49) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL8067389 | 0.83 | NPC1 (0.44) | GAASMN1; SMN2HTTLMNANPC1 | |
| SCHEMBL7979152 | 0.82 | GAA (0.62) | GAAKDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL8067282 | 0.82 | NPC1 (0.55) | SMN1; SMN2HPGDNPC1CYP1A2RAB9A | |
| SCHEMBL8065554 | 0.82 | HTT (0.36) | KDM4ESMN1; SMN2HTTLMNAHPGD | |
| SCHEMBL7965943 | 0.82 | MCHR1 (0.38) | KDM4ESMN1; SMN2HTTHPGDNPC1 | |
| SCHEMBL8065667 | 0.81 | NPC1 (0.42) | GAASMN1; SMN2HTTLMNAHPGD | |
| SCHEMBL7977366 | 0.81 | NPC1 (0.48) | SMN1; SMN2HPGDNPC1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |