Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 8/20 | 0.58 |
| ▸ | PRKCB | P05771 | 4/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.58 |
| ▸ | PRKCH | P24723 | 1/20 | 0.58 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 6/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073168 | 0.94 | PRKCA (0.58) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8065185 | 0.89 | PRKCA (0.68) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8064918 | 0.88 | PRKCA (0.67) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8317085 | 0.86 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8080083 | 0.86 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8078088 | 0.85 | PRKCA (0.58) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8161298 | 0.83 | CCNE2 (0.71) | PRKCAGSK3BKDR | |
| Hydrochloric Acid SCHEMBL8075396 | 0.82 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8065080 | 0.82 | PRKCA (0.54) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8075459 | 0.82 | PIM1 (0.70) | PRKCAPRKCBPRKCDPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |