Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075089 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8075221 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8074811 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8072736 | 1.00 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8080073 | 0.98 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8079604 | 0.98 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8079630 | 0.98 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8074778 | 0.98 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8075263 | 0.98 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8074944 | 0.96 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093345-A | PYRIMIDINE COMPOUNDS, ELECTROOPTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |
| US-5454976-A | Optical active mixture comprising a fluoro-alkyl phenyl pyrimidine compounds; high contrast ratio, fast response time; optical switches, printer shutter arrays | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-03 | — | — | US | disclosed |