Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL890416 | 0.94 | TSHR (0.49) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL25415594 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL33306 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL283894 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL5435140 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Phosphoric Acid SCHEMBL16620209 | 0.89 | TSHR (0.53) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Phosphoric Acid SCHEMBL4988141 | 0.89 | TSHR (0.53) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Bicarbonate SCHEMBL28904630 | 0.85 | TSHR (0.57) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL16863053 | 0.85 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25707 | 0.85 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630641-B1 | Method and dispenser for making dental products | DENTSPLY INT INC (US) | 2000-10-11 | — | — | EP | disclosed |
| US-5554665-A | PHOTO OR THERMAL ACRYLIC POLYMERIZATION | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0630641-A1 | Method and dispenser for making dental products | DENTSPLY INTERNATIONAL, INC. (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0183027-B1 | Biologically compatible adhesive | DENTSPLY INT INC (US) | 1994-07-13 | — | — | EP | disclosed |
| US-4657941-A | USED IN DENTISTRY | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0183027-A2 | Biologically compatible adhesive | DENTSPLY INTERNATIONAL, INC. (US) | 1986-06-04 | — | — | EP | disclosed |