Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289072 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL4289061 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL63947 | 0.87 | KDM4E (0.64) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL19244437 | 0.87 | MAPT (0.56) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL19244436 | 0.87 | MAPT (0.56) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL3536947 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL3536949 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL19244476 | 0.84 | ALDH1A1 (0.57) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL19244477 | 0.84 | ALDH1A1 (0.57) | SMN1; SMN2LMNAMAPTATMKDM4E | |
| SCHEMBL3782592 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2LMNAMAPTATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985292-A | COSMETIC OR DERMATOLOGICAL COMPOSITIONS OF THE INVENTION FOR THE TREATMENT AND CARE OF SKIN | ROUSSEL-UCLAF (FR) | 1999-11-16 | — | — | US | claimed |
| US-6133463-A | FOR USE IN COSMETIC AND DERMATOLOGICAL COMPOSITIONS FOR TREATING OR CARING FOR THE SKIN | THE BOOTS COMPANY PLC. (GB) | 2000-10-17 | — | — | US | disclosed |
| US-5985292-A | COSMETIC OR DERMATOLOGICAL COMPOSITIONS OF THE INVENTION FOR THE TREATMENT AND CARE OF SKIN | ROUSSEL-UCLAF (FR) | 1999-11-16 | — | — | US | disclosed |
| US-5656278-A | SKIN PROTECTIVE CREAM COMPRISING A MIXTURE OF A CERAMIDE AND A LINOLEIC ACID VEGETABLE OIL | THE BOOTS COMPANY PLC (GB) | 1997-08-12 | — | — | US | disclosed |
| EP-0646370-B1 | Cosmetic and dermatological compositions containing an association of ceramides and linoleic acids, their preparation | ROUSSEL UCLAF (FR) | 1996-07-24 | — | — | EP | disclosed |
| EP-0659755-A1 | Phospholipids as vectors for active molecules, their preparation and their use in cosmetic or dermatologic compositions | ROUSSEL UCLAF (FR) | 1995-06-28 | — | — | EP | disclosed |
| EP-0646370-A1 | Cosmetic and dermatological compositions containing an association of ceramides and linoleic acids, their preparation | ROUSSEL UCLAF (FR) | 1995-04-05 | — | — | EP | disclosed |