Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69464 | 0.84 | SLC6A3 (0.67) | PTPRCSLC6A3SLC6A4MAPTTSHR | |
| SCHEMBL27472310 | 0.79 | SLC6A3 (0.62) | PTPRCSLC6A3SLC6A4MAPTMITF | |
| SCHEMBL8757428 | 0.79 | MAPT (0.69) | PTPRCMAPTMITFTSHRLMNA | |
| SCHEMBL21840821 | 0.79 | NPC1 (0.71) | PTPRCMAPTMITFTSHRLMNA | |
| SCHEMBL2879389 | 0.79 | MAPT (0.65) | PTPRCMAPTMITFTSHRALDH1A1 | |
| SCHEMBL30393962 | 0.79 | MAPT (0.65) | PTPRCMAPTMITFTSHRALDH1A1 | |
| SCHEMBL8080715 | 0.78 | PTPRC (0.54) | PTPRCSLC6A3SLC6A4MAPTMITF | |
| Dimethyl Phthalate SCHEMBL790124 | 0.77 | TSHR (0.74) | SLC6A3SLC6A4MAPTTSHRLMNA | |
| Dimethyl Phthalate SCHEMBL29500970 | 0.77 | TSHR (0.74) | SLC6A3SLC6A4MAPTTSHRLMNA | |
| Dimethyl Phthalate SCHEMBL29669976 | 0.77 | TSHR (0.74) | SLC6A3SLC6A4MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149841-A | COMPOUNDS SUCH AS 3,3-BIS(4-METHOXYPHENYL)-13-OXO-3,13-DIHYDROBENZO(B)PYRANO -(4',3':6,7)NAPHTHO(2,1-B)PYRAN; ACCEPTABLE FADE RATE WITHOUT THE ADDITION OF ACIDS OR BASES AND AN ACCEPTABLE COLORATION RATE AT ROOM TEMPERATURE | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |