Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 1.00 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27351072 | 1.00 | LTB4R (1.00) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL8075759 | 0.86 | LTB4R (0.78) | LTB4R | |
| SCHEMBL27356519 | 0.86 | LTB4R (0.76) | LTB4R | |
| SCHEMBL8862137 | 0.85 | LTB4R (0.74) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL8076048 | 0.85 | LTB4R (0.75) | LTB4R | |
| SCHEMBL8862024 | 0.84 | LTB4R (0.71) | LTB4R | |
| SCHEMBL8862013 | 0.84 | LTB4R (0.71) | LTB4R | |
| SCHEMBL9333893 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9490956 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9494461 | 0.83 | LTB4R (1.00) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | claimed |
| EP-0812194-B1 | Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis | SMITHKLINE BEECHAM CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |