Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080787 | 1.00 | NPC1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2ATM | |
| SCHEMBL8180289 | 1.00 | NPC1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2ATM | |
| SCHEMBL8080793 | 0.94 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2ATM | |
| SCHEMBL11298035 | 0.85 | KCNH2 (0.54) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10717152 | 0.85 | RARB (0.61) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11615964 | 0.83 | MAP4K4 (0.49) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11561720 | 0.83 | MAP4K4 (0.49) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11562935 | 0.83 | MAP4K4 (0.49) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7468603 | 0.83 | KCNH2 (0.51) | MAPTSMN1; SMN2MEN1KMT2AADORA3 | |
| SCHEMBL10356451 | 0.83 | RARB (0.49) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646636-B1 | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0646636-A1 | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5399291-A | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |