Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615964 | 0.88 | MAP4K4 (0.49) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11562935 | 0.88 | MAP4K4 (0.49) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11561720 | 0.88 | MAP4K4 (0.49) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11565431 | 0.86 | MAP4K4 (0.50) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL11562618 | 0.85 | LMNA (0.46) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL8080787 | 0.85 | NPC1 (0.49) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8075871 | 0.85 | NPC1 (0.49) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8180289 | 0.85 | NPC1 (0.49) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11298035 | 0.84 | KCNH2 (0.54) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7468603 | 0.83 | KCNH2 (0.51) | MEN1MAPTKMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62081373-A | — | — | None | — | — | JP | disclosed |
| JP-S6281373-A | LIQUID CRYSTAL COMPOUND | ALPS ELECTRIC CO LTD | 1987-04-14 | — | — | JP | disclosed |
| US-4180475-A | POSITIVE ANISOTROPY OF DIELECTRIC CONSTANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-12-25 | — | — | US | disclosed |
| US-4145414-A | ANTIVIRAL, IMMUNOSUPPRESSIVE, ANTILEUKEMIA | THE UPJOHN COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4066570-A | OPTICAL CELLS, NEMATIC MIXTURES, LIQUID CRYSTALS | HOFFMAN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4062798-A | NEMATIC CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3997536-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-14 | — | — | US | disclosed |