Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078549 | 0.93 | — | — | |
| SCHEMBL8083586 | 0.82 | — | — | |
| SCHEMBL3891492 | 0.80 | OPRM1 (0.46) | OPRM1SPHK1TP53ADH1BADH1C | |
| SCHEMBL11291105 | 0.78 | OPRM1 (0.44) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL3886041 | 0.78 | OPRM1 (0.44) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL12483541 | 0.78 | OPRM1 (0.44) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL9866884 | 0.78 | OPRM1 (0.44) | OPRM1SPHK1TP53ADH1BADH1C | |
| SCHEMBL12484810 | 0.78 | OPRM1 (0.44) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL13279660 | 0.76 | TSHR (0.42) | OPRM1SPHK1ADH1BADH1CADH1A | |
| SCHEMBL4037962 | 0.76 | TSHR (0.42) | OPRM1SPHK1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846679-B1 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5902899-A | Process for preparing 1, 3-disubstituted urea | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0846679-A2 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |