Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | HMGCR | P04035 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579695 | 0.85 | TSHR (0.57) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL829680 | 0.85 | TSHR (0.57) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL829682 | 0.85 | TSHR (0.57) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL829681 | 0.85 | TSHR (0.57) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL9387161 | 0.83 | TSHR (0.55) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL4964807 | 0.83 | TSHR (0.55) | HSD17B10LMNATSHRNFKB1PMP22 | |
| SCHEMBL740489 | 0.83 | HSD17B10 (1.00) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL2985078 | 0.83 | HSD17B10 (1.00) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL20293445 | 0.83 | HSD17B10 (1.00) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL2803510 | 0.83 | HSD17B10 (1.00) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021551-A1 | PLANT FATTY ACID HYDROXYLASE GENES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018224-A1 | PLANT FATTY ACID HYDROXYLASE GENES | THE CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (US) | 1999-04-15 | — | — | WO | disclosed |