Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829681 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL829680 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL11579695 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL9387161 | 0.98 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL4964807 | 0.98 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL12853398 | 0.92 | GPR84 (0.64) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL6265100 | 0.92 | GPR84 (0.64) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL320497 | 0.92 | GPR84 (0.64) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL320495 | 0.92 | GPR84 (0.64) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL19427058 | 0.92 | GPR84 (0.64) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143034-B2 | Method for preparing long-chain hydroxyacids, diacids and oligomers and polymers thereof | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2012-03-27 | — | — | US | claimed |
| US-20090054610-A1 | METHOD FOR PREPARING LONG-CHAIN HYDROXYACIDS, DIACIDS AND OLIGOMERS AND POLYMERS THEREOF | SyntheZyme, LLC | 2009-02-26 | — | — | US | claimed |
| US-8158391-B2 | Production of an α-carboxyl-ω-hydroxy fatty acid using a genetically modified Candida strain | DNA TWOPOINTO, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8143034-B2 | Method for preparing long-chain hydroxyacids, diacids and oligomers and polymers thereof | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2012-03-27 | — | — | US | disclosed |
| EP-2324001-A1 | METHOD FOR PREPARING LONG-CHAIN HYDROXYACIDS, DIACIDS AND OLIGOMERS AND POLYLMERS THEREOF | Polytechnic Institute of New York University (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20100285545-A1 | BIOSYNTHETIC ROUTES TO LONG-CHAIN ALPHA,OMEGA-HYDROXYACIDS, DIACIDS AND THEIR CONVERSION TO OLIGOMERS AND POLYMERS | INC., DNA TWOPOINTO, INC. | 2010-11-11 | — | — | US | disclosed |
| WO-2010022200-A1 | METHOD FOR PREPARING LONG-CHAIN HYDROXYACIDS, DIACIDS AND OLIGOMERS AND POLYLMERS THEREOF | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20090054610-A1 | METHOD FOR PREPARING LONG-CHAIN HYDROXYACIDS, DIACIDS AND OLIGOMERS AND POLYMERS THEREOF | SyntheZyme, LLC | 2009-02-26 | — | — | US | disclosed |