Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076286 | 1.00 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL8072647 | 0.93 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL8072649 | 0.93 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL8072332 | 0.86 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL8072333 | 0.86 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL28241324 | 0.84 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL4930761 | 0.77 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL4930758 | 0.77 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL8072586 | 0.77 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL11973167 | 0.75 | CES2 (0.44) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686649-B1 | PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM | IDEMITSU KOSAN CO (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-5670580-A | POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING | IDEMITSU KOSAN CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0486293-B1 | Thermoplastic resin compositions having improved strength and method for producing them | MITSUBISHI CHEM CORP (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0686649-A1 | PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5229463-A | Blending, crosslinking propylene copolymerized with conjugated and non-connugated dienes, EPDM rubber and crystalline propylene polymer | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0486293-A2 | Thermoplastic resin compositions having improved strength and method for producing them | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-20 | — | — | EP | disclosed |