Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076295 | 1.00 | CTSK (0.48) | CTSKCTSSCA12CA1CA7 | |
| SCHEMBL4785511 | 0.95 | CTSK (0.43) | CTSKCTSS | |
| SCHEMBL6333383 | 0.89 | KDM4E (0.38) | CTSKCTSSCA1CA7 | |
| SCHEMBL6333389 | 0.89 | KDM4E (0.38) | CTSKCTSSCA1CA7 | |
| SCHEMBL6333387 | 0.89 | KDM4E (0.38) | CTSKCTSSCA1CA7 | |
| SCHEMBL15344694 | 0.89 | PLA2G2C (0.42) | CTSKCTSS | |
| SCHEMBL18648414 | 0.88 | CTSK (0.47) | CTSKCTSSCA12CA1CA7 | |
| SCHEMBL22722968 | 0.88 | CTSK (0.47) | CTSKCTSSCA12CA1CA7 | |
| SCHEMBL2013068 | 0.87 | CA1 (0.44) | CTSKCTSSCA12CA1CA7 | |
| SCHEMBL3178776 | 0.86 | MEN1 (0.54) | CTSKCTSSCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |