SCHEMBL8076324

SCHEMBL8076324

[NH]c1nc(F)nc(Nc2cc(S(=O)(=O)O)ccc2S(=O)(=O)O)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.39
CA1 P00915 4/20 0.39
CA2 P00918 4/20 0.39
CA4 P22748 4/20 0.39
CA6 P23280 4/20 0.39
CA7 P43166 4/20 0.39
CA9 Q16790 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA13 Q8N1Q1 3/20 0.39
CA3 P07451 3/20 0.35
CA5A P35218 2/20 0.35
SNCA P37840 2/20 0.33
CASP6 P55212 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHAT P28329 4/20 0.32
CASR P41180 1/20 0.32
TIMP3 P35625 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009807 0.91 CA12 (0.47) CA12CA1CA2CA4CA6
SCHEMBL13722809 0.85 CA1 (0.52) CA12CA1CA2CA4CA6
SCHEMBL14087146 0.85 CA12 (0.39) CA12CA1CA2CA4CA6
SCHEMBL13891663 0.85 CA9 (0.42) CA12CA1CA2CA4CA6
SCHEMBL9011489 0.83 TTR (0.40) CA12CA1CA2CA4CA6
SCHEMBL16560637 0.81 APEX1 (0.46) CA12CA1CA2CA4CA6
SCHEMBL10607664 0.80 CA1 (0.46) CA12CA1CA2CA4CA6
SCHEMBL9484849 0.80 CA12 (0.47) CA12CA1CA2CA4CA6
SCHEMBL4650779 0.80 SNCA (0.35) CA12CA1CA2CA4CA6
SCHEMBL21925291 0.78 CHAT (0.43) SNCACASP6ALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628606-B1 Triphendioxazine compounds, process for their preparation and their use as dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-08-23 EP disclosed
US-5484458-A POLYAMIDES OR CELLULOSE FIBERS HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-16 US disclosed
EP-0628606-A1 Triphendioxazine compounds, process for their preparation and their use as dyes HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-14 EP disclosed