Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057706 | 0.90 | TTR (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11426909 | 0.90 | CDK2 (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8076324 | 0.83 | CA12 (0.39) | CA1CA2CA12CA4CA6 | |
| SCHEMBL6562150 | 0.79 | CDK2 (0.43) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL4649932 | 0.78 | TTR (0.40) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10589718 | 0.76 | HPGDS (0.52) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL12052716 | 0.76 | HPGDS (0.45) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9799399 | 0.76 | HPGDS (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8660350 | 0.75 | HPGDS (0.40) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8055072 | 0.75 | TSHR (0.57) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559215-A | Black mixture of fibre-reactive azo dyes containing essentially a navy-blue disazo dye and an orange monoazo dye, as well as novel fibre-reactive phenylazonaphthol dyes containing A 2-(2'-sufophenylamino)-4-fluoro-1,3,5-triazin-6-ylamino group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |