Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547406 | 0.77 | TAAR1 (0.48) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL31498230 | 0.76 | TYR (0.53) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL113499 | 0.76 | TYR (0.53) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL6548345 | 0.74 | RIPK1 (0.43) | KDM4EALDH1A1TAAR1NR3C1TDP1 | |
| SCHEMBL10487810 | 0.72 | TAAR1 (0.46) | KDM4EALDH1A1PYCR1TAAR1 | |
| SCHEMBL14676492 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL598097 | 0.71 | TAAR1 (0.43) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL11282435 | 0.70 | KMT2A (0.37) | KDM4EALDH1A1PYCR1KMT2ATAAR1 | |
| SCHEMBL10969479 | 0.70 | CYP19A1 (0.47) | ALDH1A1TDP1RAB9ALMNAHTT | |
| SCHEMBL1611590 | 0.70 | TAAR1 (0.42) | KDM4EALDH1A1PYCR1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096680-A | REUSABLE ALUMINUM FRIEDEL-CRAFTS CATALYSTS; FORMED FROM AN ALUMINUM TRIHALIDE, ALKALI METAL HALIDE OR PSEUDOHALIDE, ALKALINE EARTH METAL HALIDE, QUATERNARY AMMONIUM, PHOSPHONIUM AND/OR SULFONIUM SALT AND AN AROMATIC HYDROCARBON | ALBEMARLE CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| WO-1999054038-A1 | LIQUID CLATHRATE COMPOSITIONS | ALBEMARLE CORPORATION (US) | 1999-10-28 | — | — | WO | disclosed |
| US-5859302-A | Processes employing reusable aluminum catalysts | ALBEMARLE CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0838447-A1 | Processes employing reusable aluminum catalysts | ALBEMARLE CORPORATION (US) | 1998-04-29 | — | — | EP | disclosed |