Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076718 | 0.90 | BACE1 (0.37) | BACE1PRNPRXFP1KDM4EPOLB | |
| SCHEMBL8089824 | 0.88 | PRNP (0.34) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8076742 | 0.85 | QPCT (0.41) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8084848 | 0.85 | PRNP (0.37) | BACE1PRNPRXFP1KDM4EPOLB | |
| SCHEMBL8084787 | 0.80 | KMT2A (0.39) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8084735 | 0.78 | ALDH1A1 (0.36) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8084411 | 0.76 | KMT2A (0.37) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8084777 | 0.76 | PRNP (0.34) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8088277 | 0.75 | PRNP (0.33) | PRNPRXFP1KDM4EPOLBKMT2A | |
| SCHEMBL8088244 | 0.75 | MAPKAPK2 (0.38) | PRNPRXFP1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |