Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807689 | 1.00 | GJB2 (0.31) | GJB2USP2ALDH1A1POLBALOX15 | |
| SCHEMBL10112577 | 0.83 | DOT1L (0.36) | GJB2USP2ALDH1A1POLBALOX15 | |
| SCHEMBL4970295 | 0.81 | GJB2 (0.31) | GJB2 | |
| SCHEMBL4970178 | 0.81 | GJB2 (0.31) | GJB2 | |
| SCHEMBL807685 | 0.76 | — | — | |
| SCHEMBL4970292 | 0.72 | — | — | |
| SCHEMBL16631585 | 0.71 | GJB2 (0.30) | GJB2 | |
| SCHEMBL15259029 | 0.70 | PDE2A (0.33) | — | |
| SCHEMBL19292097 | 0.70 | PDE2A (0.33) | — | |
| SCHEMBL15259053 | 0.70 | PDE2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037038-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-22 | — | — | WO | disclosed |