Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326400 | 0.88 | ABCC9 (0.43) | ABCB1ABCC9KDM4E | |
| SCHEMBL7325020 | 0.86 | ABCC9 (0.44) | ABCB1ABCC9KDM4E | |
| SCHEMBL7325525 | 0.85 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL8088871 | 0.84 | ABCC9 (0.38) | ABCB1ABCC9KDM4E | |
| SCHEMBL7329956 | 0.83 | ABCB1 (0.38) | ABCB1ABCC9KDM4E | |
| SCHEMBL7331068 | 0.82 | ABCB1 (0.38) | ABCB1ABCC9KDM4E | |
| SCHEMBL7332374 | 0.80 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL7328970 | 0.80 | ABCC9 (0.42) | ABCB1ABCC9KDM4E | |
| SCHEMBL8076984 | 0.80 | ABCC9 (0.56) | ABCB1ABCC9KDM4EABCC8KCNJ11 | |
| SCHEMBL10519818 | 0.79 | ABCC9 (0.44) | ABCB1ABCC9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |