Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072512 | 1.00 | LMNA (0.41) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL9235255 | 0.85 | LMNA (0.44) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL468798 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL27182003 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL468790 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL468705 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL11225324 | 0.83 | PDE4A (0.50) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL11525537 | 0.81 | LMNA (0.41) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| Acetic Acid SCHEMBL5160517 | 0.81 | PDE4A (0.48) | LMNAL3MBTL1KDM4EPDE4ATDP1 | |
| SCHEMBL2729688 | 0.81 | USP2 (0.41) | LMNAL3MBTL1KDM4EPDE4ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721956-B1 | 21-SUBSTITUTED STEROID COMPOUND | NISSIN FOOD PRODUCTS LTD (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-5945404-A | ANTIINFLAMMATORY AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0721956-A1 | 21-SUBSTITUTED STEROID COMPOUND | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1996-07-17 | — | — | EP | disclosed |