SCHEMBL8077501

SCHEMBL8077501

O=C(O)CN(CC(=O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.41
BLM P54132 3/20 0.41
LMNA P02545 3/20 0.41
TSHR P16473 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
EYA2 O00167 1/20 0.41
APP P05067 1/20 0.41
ACE P12821 1/20 0.41
PMP22 Q01453 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ALOX15 P16050 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30712164 0.85 TDP1 (0.40) TDP1BLMLMNATSHRMEN1
SCHEMBL1278674 0.83 TDP1 (0.39) TDP1BLMLMNATSHRMEN1
SCHEMBL1278695 0.81 TDP1 (0.37) TDP1BLMLMNATSHRMEN1
SCHEMBL9580132 0.79 ALDH1A1 (0.38) TDP1BLMLMNATSHRMEN1
SCHEMBL3802016 0.77 TDP1 (0.41) TDP1BLMLMNATSHRMEN1
Nitrilotriacetic Acid SCHEMBL4638079 0.73 TDP1 (0.58) TDP1BLMLMNATSHRMEN1
SCHEMBL527443 0.72 MVD (0.40) TDP1BLMLMNATSHRMEN1
Ammonia Solution, Strong SCHEMBL7761771 0.70 MVD (0.39) TDP1BLMLMNATSHRMEN1
SCHEMBL8432722 0.69 TDP1 (0.35) TDP1BLMLMNATSHRMEN1
Phosphoric Acid SCHEMBL30277662 0.69 MVD (0.41) TDP1BLMLMNATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1480460-A Method for preparing N-phosphine carboxymerhyl-glycin 上海开普精细化工有限公司 2004-03-10 CN disclosed
EP-1024699-A1 A HERBICIDAL COMPOSITION COMPRISING GLYPHOSATE AND AN N-ACYLSARCOSINATE Parker, Brian (IE) 2000-08-09 EP disclosed
WO-1999021424-A1 A HERBICIDAL COMPOSITION COMPRISING GLYPHOSATE (N-PHOSPHONOMETHYL GLYCINE) AND AN N-ACYL SARCOSINATE BARCLAY CHEMICALS (R & D) LIMITED (IE) 1999-05-06 WO disclosed
WO-1999021423-A1 A HERBICIDAL COMPOSITION COMPRISING GLYPHOSATE AND AN N-ACYLSARCOSINATE PARKER BRIAN (IE) 1999-05-06 WO disclosed
EP-0399985-B1 Process for producing N-phosphonomethylglycine MONSANTO CO (US) 1995-01-04 EP disclosed
EP-0399985-A2 Process for producing N-phosphonomethylglycine MONSANTO COMPANY (US) 1990-11-28 EP disclosed
US-4937376-A Using oxidation catalyst mixture of metal salt, and (hydro)quinone MONSANTO COMPANY (US) 1990-06-26 US disclosed
US-4851131-A OXIDATION WITH TRANSITION METAL CATALYSTS MONSANTO COMPANY (US) 1989-07-25 US disclosed