SCHEMBL8077526

SCHEMBL8077526

COC(=O)C1(Br)C=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7687683 0.80 POLB (0.33) MEN1KMT2A
SCHEMBL4524582 0.78
SCHEMBL10532356 0.78
SCHEMBL5347884 0.76 MEN1 (0.33) MEN1KMT2A
SCHEMBL28231867 0.76 MAPK1 (0.32) MEN1KMT2A
SCHEMBL28386150 0.75
Ethylene SCHEMBL10741250 0.74
SCHEMBL6106227 0.74 NPSR1 (0.31)
SCHEMBL25263047 0.73
SCHEMBL6891454 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107200727-B Anthracene-indenofluorene derivative containing pyrimidine, pyrazine or triazine group and preparation method and application thereof 华南理工大学 2020-02-18 CN disclosed
EP-0701819-B1 Novel compositions containing sertraline and a 5-HT1D receptor agonist or antagonist PFIZER (US) 2000-08-16 EP disclosed
EP-0701819-A2 Novel compositions containing sertraline and a 5-HT1D receptor agonist or antagonist PFIZER INC. (US) 1996-03-20 EP disclosed