Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39547 | 0.88 | — | — | |
| SCHEMBL29565534 | 0.88 | — | — | |
| Sulfuric Acid SCHEMBL9293766 | 0.86 | GABRA1 (0.44) | GAACA12CA1CA2CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL27637031 | 0.85 | CYP3A4 (0.47) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Iodide SCHEMBL29238182 | 0.85 | CYP3A4 (0.47) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Water SCHEMBL17512841 | 0.85 | CYP3A4 (0.47) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL1585890 | 0.85 | CYP3A4 (0.48) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Bromide SCHEMBL28472529 | 0.85 | CYP3A4 (0.47) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Water SCHEMBL27919614 | 0.85 | CYP3A4 (0.47) | GAACYP2C9FDPSGABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL2872325 | 0.85 | CYP3A4 (0.48) | GAACYP2C9FDPSGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837692-B1 | CLOSTRIDIUM DIFFICILE TOXINS AND TOXOIDS AS MUCOSAL ADJUVANTS | ORAVAX INC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5919463-A | INDUCING IMMUNE RESPONSE IN MAMMALS | ORAVAX, INC. (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0837692-A1 | CLOSTRIDIUM DIFFICILE TOXINS AS MUCOSAL ADJUVANTS | ORAVAX, INC. (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0837692-A4 | — | — | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002836-A1 | CLOSTRIDIUM DIFFICILE TOXINS AS MUCOSAL ADJUVANTS | ORAVAX, INC. (US) | 1997-01-30 | — | — | WO | disclosed |