Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077696 | 1.00 | AR (0.54) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8074335 | 0.86 | SRD5A1 (0.53) | SRD5A2SRD5A1 | |
| SCHEMBL8074330 | 0.86 | SRD5A1 (0.53) | SRD5A2SRD5A1 | |
| SCHEMBL8079259 | 0.79 | NR1H4 (0.40) | — | |
| SCHEMBL8498127 | 0.78 | AR (0.57) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8903390 | 0.77 | AR (0.49) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8904418 | 0.77 | AR (0.53) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL14184859 | 0.76 | AR (0.54) | ARSRD5A2KCNH2 | |
| SCHEMBL8496653 | 0.76 | AR (0.54) | ARSRD5A2KCNH2SRD5A1 | |
| SCHEMBL8765894 | 0.76 | AR (0.60) | ARSRD5A2KCNH2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641208-B1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 2000-08-02 | — | — | EP | claimed |