Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077762 | 1.00 | ALOX15 (0.45) | ALOX15CHRNA7CA12CA1CA2 | |
| Bromide SCHEMBL7976070 | 0.99 | ALOX15 (0.44) | ALOX15CHRNA7CA12CA1CA2 | |
| Bromide SCHEMBL7654939 | 0.89 | ALOX15 (0.45) | ALOX15CHRNA7CHRM2CHRM1CHRM3 | |
| Bromide SCHEMBL7654935 | 0.89 | ALOX15 (0.45) | ALOX15CHRNA7CHRM2CHRM1CHRM3 | |
| SCHEMBL7972296 | 0.89 | CHRNA7 (0.39) | CHRNA7CA12CA1CA2CA9 | |
| Bromide SCHEMBL7653865 | 0.88 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1CHRM3KCNH2 | |
| Bromide SCHEMBL7653869 | 0.88 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1CHRM3KCNH2 | |
| Bromide SCHEMBL7975609 | 0.88 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1CHRM3KCNH2 | |
| Bromide SCHEMBL8082351 | 0.88 | ALOX15 (0.44) | ALOX15CHRNA7CHRM2CHRM1CHRM3 | |
| Bromide SCHEMBL7972238 | 0.88 | ALOX15 (0.44) | ALOX15CHRNA7CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025099-A1 | BIS-QUATERNARY AMMONIUM DERIVATIVES AS NEUROMUSCULAR RELAXANTS | Gyermek, Laszlo (US) | 2000-08-09 | — | — | EP | claimed |
| WO-1999021854-A1 | BIS-QUATERNARY AMMONIUM DERIVATIVES AS NEUROMUSCULAR RELAXANTS | NEWLAXANT LLC (US) | 1999-05-06 | — | — | WO | claimed |