SCHEMBL8078151

SCHEMBL8078151

O=C(OC/C=C\COC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.61
MAPK1 P28482 1/20 0.59
HIF1A Q16665 1/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
KMT2A Q03164 1/20 0.59
LMNA P02545 2/20 0.57
ALDH1A1 P00352 2/20 0.57
TK1 P04183 1/20 0.55
F2 P00734 1/20 0.54
TSHR P16473 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8522569 1.00 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL8522570 1.00 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11612353 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11570740 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11570739 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL10540715 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11570806 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11570808 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL9838229 0.92 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11571204 0.91 TDP1 (0.52) TDP1MAPK1HIF1ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011664-B2 Functionalized nitrile rubbers and the production thereof ARLANXEO DEUTSCHLAND GMBH (DE) 2018-07-03 US claimed
US-20170190806-A1 FUNCTIONALISED NITRILE RUBBERS AND THE PRODUCTION THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2017-07-06 US claimed
EP-2670782-A1 FUNCTIONALISED NITRILE RUBBERS AND THE PRODUCTION THEREOF LANXESS Deutschland GmbH (DE) 2013-12-11 EP claimed
EP-2484700-B1 Functionalised nitrile rubbers and their manufacture LANXESS DEUTSCHLAND GMBH (DE) 2013-10-09 EP claimed
WO-2012104183-A1 FUNCTIONALISED NITRILE RUBBERS AND THE PRODUCTION THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2012-08-09 WO claimed
EP-2484700-A1 Functionalised nitrile rubbers and their manufacture LANXESS Deutschland GmbH (DE) 2012-08-08 EP claimed
EP-4149912-B1 PROCESS FOR PREPARING DIENE FIRMENICH & CIE (CH) 2025-04-30 EP disclosed
US-12103898-B2 Process for preparing diene FIRMENICH SA (CH) 2024-10-01 US disclosed
US-20230265025-A1 PROCESS FOR PREPARING DIENE FIRMENICH SA (CH) 2023-08-24 US disclosed
US-11713361-B2 Hydrogenation catalyst compositions and their use for hydrogenation of nitrile rubber ARLANXEO DEUTSCHLAND GMBH (DE) 2023-08-01 US disclosed
US-11713361-B2 Hydrogenation catalyst compositions and their use for hydrogenation of nitrile rubber ARLANXEO DEUTSCHLAND GMBH (DE) 2023-08-01 US disclosed
CN-115916732-A Process for preparing dienes 弗门尼舍有限公司 2023-04-04 CN disclosed
EP-4149912-A1 PROCESS FOR PREPARING DIENE Firmenich SA (CH) 2023-03-22 EP disclosed
WO-2013056461-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2013-04-25 WO disclosed
WO-2013056400-A1 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2013-04-25 WO disclosed
WO-2013057289-A2 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2013-04-25 WO disclosed
WO-2013057295-A2 CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2013-04-25 WO disclosed
EP-2484700-A1 Functionalised nitrile rubbers and their manufacture LANXESS Deutschland GmbH (DE) 2012-08-08 EP disclosed
EP-2484700-A1 Functionalised nitrile rubbers and their manufacture LANXESS Deutschland GmbH (DE) 2012-08-08 EP disclosed
WO-2009030733-A1 METHOD FOR THE SYNTHESIS OF 4-ALKOXY-, 4-HYDROXY- AND 4-ARYLOXY-SUBSTITUTED TETRAHYDRO-FURO[3,4-B]FURAN-2(3H)-ONE COMPOUNDS DSM IP ASSETS B.V. (NL) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265025-A1 PROCESS FOR PREPARING DIENE FDFT1, SQLE, DHPS TDP1 3470/4885MAPK1 2434/4885HIF1A 1813/4885
US-12103898-B2 Process for preparing diene FDFT1, SQLE, DHPS TDP1 3470/4885MAPK1 2434/4885HIF1A 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.