SCHEMBL807828

SCHEMBL807828

Bc1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1cc(Br)ccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.49
PTPRC P08575 1/20 0.38
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
OPRK1 P41145 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP2A6 P11509 1/20 0.31
AKR1A1 P14550 1/20 0.31
AKR1B1 P15121 1/20 0.31
S100A4 P26447 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846947 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29399278 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29511719 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL783450 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29602609 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29530902 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL783463 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29397249 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL996751 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E
SCHEMBL29574412 0.89 PDK2 (0.58) PDK2PTPRCOPRM1OPRD1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012034626-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 WO disclosed
WO-2007043354-A9 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2007-06-07 WO disclosed