Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 17/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.38 |
| ▸ | ATR | Q13535 | 14/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 14/20 | 0.38 |
| ▸ | ATM | Q13315 | 9/20 | 0.38 |
| ▸ | MTOR | P42345 | 5/20 | 0.36 |
| ▸ | SERPINA2 | P20848 | 2/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796977 | 0.78 | PRKDC (0.48) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15123762 | 0.78 | PRKDC (0.48) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL797021 | 0.76 | PRKDC (0.46) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL797022 | 0.76 | PRKDC (0.46) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131813 | 0.74 | PRKDC (0.54) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131816 | 0.73 | PRKDC (0.45) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131817 | 0.73 | PRKDC (0.45) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131814 | 0.68 | MTOR (0.36) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL807841 | 0.62 | ROCK2 (0.32) | — | |
| SCHEMBL15131819 | 0.62 | PRKDC (0.55) | PRKDCPIK3CBATRATRIPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034526-A1 | FUSED HETEROARYLS AND THEIR USES | HUTCHISON MEDIPHARMA LIMITED (CN) | 2012-03-22 | — | — | WO | disclosed |