Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019252 | 1.00 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL8846295 | 0.88 | HTR6 (0.31) | HTR2AHTR6 | |
| SCHEMBL6566244 | 0.87 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL8845784 | 0.83 | — | — | |
| SCHEMBL8467163 | 0.83 | MEN1 (0.33) | SIGMAR1MEN1KMT2A | |
| SCHEMBL8749938 | 0.78 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL3761123 | 0.78 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL4456972 | 0.78 | HTR2A (0.42) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL8383847 | 0.78 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 | |
| SCHEMBL5183873 | 0.78 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260343-A | Single metallocene catalyst containing salicylaldimine ligand and preparation method and application thereof | 中国科学技术大学 | 2022-11-01 | — | — | CN | disclosed |
| US-6114556-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 2000-09-05 | — | — | US | disclosed |