Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807847 | 1.00 | PDK2 (0.48) | PDK2MAOAMAOBKCNN4KCNA5 | |
| SCHEMBL19443822 | 0.96 | PDK2 (0.44) | PDK2MAOAMAOBKCNN4KCNA5 | |
| SCHEMBL19890955 | 0.93 | PDK2 (0.45) | PDK2MAOAMAOBKCNN4KCNA5 | |
| SCHEMBL20779851 | 0.92 | PDK2 (0.39) | PDK2MAOAMAOBKCNN4KCNA5 | |
| SCHEMBL21442823 | 0.91 | PDK2 (0.41) | PDK2KCNN4KCNA5PGR | |
| SCHEMBL16186425 | 0.90 | PDK2 (0.41) | PDK2KCNN4KCNA5 | |
| SCHEMBL23155253 | 0.89 | PDK2 (0.40) | PDK2MAOAMAOBKCNN4KCNA5 | |
| SCHEMBL16996418 | 0.89 | PDK2 (0.40) | PDK2MAOAMAOBKDM4EMAPT | |
| SCHEMBL808121 | 0.89 | PDK2 (0.48) | PDK2MAOAMAOBPGRTSHR | |
| SCHEMBL19754291 | 0.89 | PDK2 (0.45) | PDK2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9947874-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-20160190447-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-9312495-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| EP-2616428-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-12-24 | — | — | EP | disclosed |
| US-20130207046-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012034627-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160190447-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | PDK2 1024/4885MAOA 582/4885MAOB 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.