Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761498 | 0.83 | MAOB (0.70) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL8028721 | 0.83 | MAOB (0.70) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL3482694 | 0.82 | TDP1 (0.64) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL9784265 | 0.82 | TDP1 (0.64) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL2629379 | 0.82 | HIF1A (0.49) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL10883892 | 0.82 | SMN1; SMN2 (0.83) | SMN1; SMN2TSHRMAPTALDH1A1HPGD | |
| SCHEMBL8672714 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2TDP1ALDH1A1NPC1RAB9A | |
| SCHEMBL15723550 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL204685 | 0.81 | ALDH1A1 (0.76) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 | |
| SCHEMBL49650 | 0.81 | ALDH1A1 (0.76) | SMN1; SMN2TDP1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4059826-A | — | — | None | — | — | JP | disclosed |
| US-6137008-A | USEFUL AS STARTING MATERIAL FOR MAKING FLEXIBLE AROMATIC POLYAMIDES OR POLYIMIDES | NATIONAL SCIENCE COUNCIL (TW) | 2000-10-24 | — | — | US | disclosed |
| EP-0562824-B1 | Thermal recording material | FUJI PHOTO FILM CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5464804-A | Heat sensitive color layer with electron donor, colorless dye is black color aminofluoran, amino compound and isocyanate compound | FUJI PHOTO FILM CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5288688-A | Comprising electron-donating colorless dye, isocyanate and amino compounds; antifogging, discoloration inhibition, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| JP-H0459826-A | AROMATIC POLYIMIDE MOLDABLE IN MELT | HITACHI CHEM CO LTD | 1992-02-26 | — | — | JP | disclosed |