Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187302 | 1.00 | ESR2 (0.44) | ESR2ESR1CYP3A4KDM4EMEN1 | |
| SCHEMBL6131967 | 0.83 | ESR2 (0.38) | ESR2ESR1CYP3A4KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL11553193 | 0.81 | ESR2 (0.37) | ESR2ESR1CYP3A4KDM4EMEN1 | |
| SCHEMBL6860743 | 0.80 | CYP2D6 (0.37) | ESR2ESR1CYP3A4KDM4EMEN1 | |
| SCHEMBL31145247 | 0.80 | ESR2 (0.53) | ESR2ESR1CYP3A4ALDH1A1MAPT | |
| SCHEMBL24364303 | 0.80 | ESR2 (0.53) | ESR2ESR1CYP3A4ALDH1A1MAPT | |
| SCHEMBL29324808 | 0.80 | ESR2 (0.53) | ESR2ESR1CYP3A4ALDH1A1MAPT | |
| SCHEMBL19580315 | 0.75 | CHRNB2 (0.50) | ESR2ESR1MEN1KMT2ACYP2C9 | |
| SCHEMBL18708238 | 0.74 | MAPT (0.47) | KDM4EALDH1A1LMNAMAPTRECQL | |
| SCHEMBL3442854 | 0.74 | MEN1 (0.42) | CYP3A4MEN1ALDH1A1LMNACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466142-B2 | Cephalotaxus esters, methods of synthesis, and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-18 | — | — | US | disclosed |
| US-6084118-A | Sunscreening composition comprising natural products of a marine hydroid and derivatives thereof | LINDQUIST NIELS L (US) | 2000-07-04 | — | — | US | disclosed |
| US-5980920-A | Antioxidant compositions | LINDQUIST NIELS L (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0936895-A4 | — | — | 1999-09-08 | — | — | EP | disclosed |
| EP-0936895-A1 | SUNSCREENING COMPOSITIONS COMPRISING NATURAL PRODUCTS OF A MARINE HYDROID, AND DERIVATIVES THEREOF | Lindquist, Niels L. (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5905158-A | Sunscreening compositions comprising natural products of a marine hydroid, and derivative thereof | LINDQUIST NIELS L (US) | 1999-05-18 | — | — | US | disclosed |
| US-5705146-A | Sunscreening compositions comprising natural products of a marine hydroid, and derivatives thereof | LINDQUIST NIELS L (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997019671-A1 | SUNSCREENING COMPOSITIONS COMPRISING NATURAL PRODUCTS OF A MARINE HYDROID, AND DERIVATIVES THEREOF | LINDQUIST NIELS L (US) | 1997-06-05 | — | — | WO | disclosed |