Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986240 | 0.94 | TSHR (0.37) | TSHRACHEALDH1A1CYP3A4 | |
| SCHEMBL2023881 | 0.85 | TSHR (0.41) | TSHRACHE | |
| SCHEMBL2023626 | 0.85 | TSHR (0.38) | TSHRACHEALDH1A1CYP3A4GAA | |
| SCHEMBL8537810 | 0.84 | TSHR (0.48) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL27940590 | 0.83 | TSHR (0.42) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL3792860 | 0.82 | TSHR (0.61) | TSHRACHEALDH1A1CYP3A4 | |
| SCHEMBL8536455 | 0.82 | TSHR (0.52) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL5484676 | 0.80 | TSHR (0.53) | TSHRACHEALDH1A1TDP1 | |
| SCHEMBL1375008 | 0.79 | TSHR (0.42) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL1547902 | 0.78 | TSHR (0.39) | TSHRACHEALDH1A1CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675885-B1 | NOVEL RING OPENING MONOMERS | COMMW SCIENT IND RES ORG (AU) | 2000-09-06 | — | — | EP | disclosed |
| US-5665839-A | Ring opening monomers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-09-09 | — | — | US | disclosed |
| EP-0675885-A4 | — | — | 1995-10-25 | — | — | EP | disclosed |
| EP-0675885-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014792-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-07-07 | — | — | WO | disclosed |
| US-5248717-A | Hydroxy-functional polyester diluents as additives in coating compositions | THE SHERWIN-WILLIAMS COMPANY (US) | 1993-09-28 | — | — | US | disclosed |