Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536455 | 0.98 | TSHR (0.52) | TSHRACHENAAACYP4F2CYP4A11 | |
| SCHEMBL5709205 | 0.94 | TSHR (0.46) | TSHRACHENAAACYP4F2CYP4A11 | |
| SCHEMBL9646938 | 0.92 | TSHR (0.55) | TSHRACHENAAATHRBALDH1A1 | |
| SCHEMBL19456885 | 0.87 | TSHR (0.50) | TSHRACHENAAATHRBALDH1A1 | |
| Ethylene Glycol SCHEMBL5469504 | 0.87 | TSHR (0.62) | TSHRACHENAAATHRBALDH1A1 | |
| SCHEMBL374970 | 0.86 | TSHR (0.66) | TSHRACHENAAAALDH1A1HPGD | |
| SCHEMBL173351 | 0.85 | TSHR (0.41) | TSHRACHENAAATHRBALDH1A1 | |
| SCHEMBL8079396 | 0.84 | TSHR (0.40) | TSHRACHECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3627611 | 0.84 | TSHR (0.69) | TSHRACHENAAAALDH1A1RAD52 | |
| SCHEMBL11803516 | 0.84 | TSHR (0.69) | TSHRACHENAAAALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101552-B | Copolymer ceramic body reinforcing agent based on cyclodextrin and ATRP preparation method thereof | 湖南辰砾新材料有限公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-0557131-B1 | Process for making a polymer-supported catalyst | ROHM & HAAS (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0557131-A2 | Polymer-supported catalysts | ROHM AND HAAS COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |