Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.69 |
| ▸ | HTR2C | P28335 | 2/20 | 0.69 |
| ▸ | HRH1 | P35367 | 2/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 2/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188841 | 1.00 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL17694756 | 0.90 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL10064914 | 0.90 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL5012040 | 0.86 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL2208714 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL2211203 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL2212613 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL5114671 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL10031213 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL7996118 | 0.85 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761478-B1 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARM FINE CHEMICALS SRL (IT) | 2008-09-03 | — | — | EP | disclosed |
| US-20080031932-A1 | Transdermal atomoxetine formulations and associated methods | WATSON LABORATORIES, INC. (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-01-03 | — | — | US | disclosed |
| WO-2006037055-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | SLC6A2, SLC6A4, SLC6A3 | SLC6A2 1/4885SLC6A4 2/4885SLC6A3 3/4885 |
| US-20080031932-A1 | Transdermal atomoxetine formulations and associated methods | SLC6A4, SLC6A2, CYP2D6 | SLC6A2 2/4885SLC6A4 1/4885SLC6A3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.