Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079491 | 1.00 | SRD5A2 (0.37) | SRD5A2SRD5A1CYP19A1 | |
| SCHEMBL15121547 | 0.79 | SRD5A1 (0.38) | SRD5A2SRD5A1CYP19A1 | |
| SCHEMBL3869935 | 0.79 | SRD5A1 (0.38) | SRD5A2SRD5A1CYP19A1 | |
| SCHEMBL3869928 | 0.79 | SRD5A1 (0.38) | SRD5A2SRD5A1CYP19A1 | |
| SCHEMBL8544903 | 0.77 | GPBAR1 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL8540006 | 0.77 | GPBAR1 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL22926300 | 0.76 | SRD5A2 (0.39) | SRD5A2CYP19A1 | |
| SCHEMBL518237 | 0.75 | SRD5A2 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL518238 | 0.75 | SRD5A2 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL536894 | 0.74 | CDK5 (0.49) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902790-B1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN SPA (IT) | 2000-08-16 | — | — | EP | disclosed |
| EP-0902790-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997040062-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-10-30 | — | — | WO | disclosed |