Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540006 | 1.00 | GPBAR1 (0.54) | GPBAR1SRD5A1SRD5A2AKR1B10AKR1B1 | |
| SCHEMBL14160671 | 0.82 | SRD5A1 (0.66) | SRD5A1SRD5A2LMNACDC25A | |
| SCHEMBL7705921 | 0.80 | GPBAR1 (0.64) | GPBAR1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL8677504 | 0.79 | GPBAR1 (0.69) | GPBAR1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL8542081 | 0.79 | GPBAR1 (0.51) | GPBAR1SRD5A1SRD5A2 | |
| SCHEMBL8544324 | 0.77 | GPBAR1 (0.54) | GPBAR1SRD5A1SRD5A2AKR1B10AKR1B1 | |
| SCHEMBL8079488 | 0.77 | SRD5A2 (0.37) | SRD5A1SRD5A2 | |
| SCHEMBL8079491 | 0.77 | SRD5A2 (0.37) | SRD5A1SRD5A2 | |
| SCHEMBL3869928 | 0.72 | SRD5A1 (0.38) | SRD5A1SRD5A2KMT2A | |
| SCHEMBL15121547 | 0.72 | SRD5A1 (0.38) | SRD5A1SRD5A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760045-A | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. (US) | 1998-06-02 | — | — | US | claimed |