Tyrosine

Tyrosine

SCHEMBL8079541

CC(C)[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.C[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.53
ALOX15 P16050 2/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
KMT2A Q03164 1/20 0.42
PTGS1 P23219 2/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
XIAP P98170 1/20 0.40
PCNA P12004 1/20 0.39
TPH1 P17752 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
EGFR P00533 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
HTR2A P28223 1/20 0.39
PTGS2 P35354 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL26977289 0.94 SLC7A5 (0.60) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL20680472 0.89 SLC7A5 (0.67) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL16820324 0.87 SLC7A5 (0.71) SLC7A5ALOX15PTGS1ALPIPKM
Tyrosine SCHEMBL1931272 0.87 THRB (0.43) SLC7A5
Tyrosine SCHEMBL6141122 0.87 THRB (0.43) SLC7A5
Tyrosine SCHEMBL3443100 0.86 SLC7A5 (0.58) SLC7A5ALOX15PTGS1ALPIPKM
Tyrosine SCHEMBL3909629 0.86 SLC7A5 (0.50) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL3909625 0.86 SLC7A5 (0.50) SLC7A5ALOX15BLMPMP22KMT2A
Tyrosine SCHEMBL27559867 0.86 SLC7A5 (0.47) SLC7A5ALOX15PTGS1ALPIPKM
Tyrosine SCHEMBL8588119 0.85 SLC7A5 (0.49) SLC7A5ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668772-B1 SPECIFIC IMMUNE SYSTEM MODULATION UNIV YALE (US) 2000-08-30 EP disclosed