⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191431 | 1.00 | — | — | |
| SCHEMBL9792876 | 1.00 | — | — | |
| SCHEMBL8109464 | 1.00 | — | — | |
| SCHEMBL8109466 | 1.00 | — | — | |
| SCHEMBL11007855 | 0.83 | GBA2 (0.30) | — | |
| SCHEMBL6857765 | 0.83 | GBA2 (0.30) | — | |
| SCHEMBL19174844 | 0.80 | — | — | |
| SCHEMBL19136724 | 0.80 | — | — | |
| SCHEMBL15024141 | 0.77 | — | — | |
| SCHEMBL1973814 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503652-B | Chemical total synthesis preparation method of crotonaldehyde diterpene Prostratin | 西安交通大学 | 2020-08-28 | — | — | CN | claimed |
| CN-108503652-A | A kind of fully synthetic preparation method of chemistry of crotons alkane diterpene Prostratin | 西安交通大学 | 2018-09-07 | — | — | CN | claimed |
| CN-115536530-B | Chemical total synthesis method of Vulgarisin type tetracyclic diterpenoid compound | 浙江大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-114560760-B | Synthesis method of euphorbiaceae diterpene Pepluanol A | 浙江大学杭州国际科创中心 | 2024-05-17 | — | — | CN | disclosed |
| WO-2023142618-A1 | SYNTHESIS METHOD FOR EUPHORBIA DITERPENOID PEPLUANOL A | 浙江大学杭州国际科创中心 | 2023-08-03 | — | — | WO | disclosed |
| CN-115536530-A | Chemical total synthesis method of Vulgarisin type tetracyclic diterpenoid compound | 浙江大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-114560760-A | Method for synthesizing diterpene Pepluanol A in Euphorbiaceae | 浙江大学杭州国际科创中心 | 2022-05-31 | — | — | CN | disclosed |
| CN-108503652-B | Chemical total synthesis preparation method of crotonaldehyde diterpene Prostratin | 西安交通大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-108503652-B | Chemical total synthesis preparation method of crotonaldehyde diterpene Prostratin | 西安交通大学 | 2020-08-28 | — | — | CN | disclosed |
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| CN-108503652-A | A kind of fully synthetic preparation method of chemistry of crotons alkane diterpene Prostratin | 西安交通大学 | 2018-09-07 | — | — | CN | disclosed |
| EP-0580667-B1 | ENANTIOMERS OF CYCLOPENTENE DERIVATIVES | CHIROTECH TECHNOLOGY LTD (GB) | 2000-09-20 | — | — | EP | disclosed |
| US-5063233-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |
| US-4954504-A | Hypotensive agents, psychotic disorders | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0267878-A1 | N9-cyclopentyl-substituted adenine derivatives | CIBA-GEIGY AG (CH) | 1988-05-18 | — | — | EP | disclosed |