Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21447568 | 0.86 | HSD11B1 (0.52) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL5972547 | 0.86 | CYP2C19 (0.61) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL313012 | 0.84 | POLB (0.55) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL5972813 | 0.84 | SMN1; SMN2 (0.51) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL28100629 | 0.83 | HSD11B1 (0.50) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL4619371 | 0.82 | SMN1; SMN2 (0.54) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL28549853 | 0.82 | SMN1; SMN2 (0.50) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL8695219 | 0.81 | KCNN4 (0.50) | POLBSMN1; SMN2CYP2C19HIF1AKMT2A | |
| SCHEMBL11839587 | 0.81 | SMN1; SMN2 (0.49) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL28137288 | 0.81 | SMN1; SMN2 (0.49) | HSD11B1POLBSMN1; SMN2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070841-C | Carboxylic acid derivatives, their prepn. and their use | BASF AG (DE) | 2001-09-12 | — | — | CN | disclosed |
| EP-0862550-B1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| CN-1200720-A | Carboxylic acid derivatives, their preparation and use | BASF AG (DE) | 1998-12-02 | — | — | CN | disclosed |
| EP-0862550-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997009294-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |