Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 6/20 | 0.51 |
| ▸ | IDH1 | O75874 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | IL6ST | P40189 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17146814 | 0.91 | NAAA (0.57) | NAAAIDH1PPARAFAAHALDH1A1 | |
| SCHEMBL6334745 | 0.89 | NAAA (0.57) | NAAAIDH1PPARAFAAH | |
| SCHEMBL21978161 | 0.89 | NAAA (0.51) | NAAAIDH1PPARAFAAHHDAC1 | |
| SCHEMBL345276 | 0.89 | NAAA (0.57) | NAAAIDH1PPARAFAAH | |
| SCHEMBL345275 | 0.89 | NAAA (0.57) | NAAAIDH1PPARAFAAH | |
| SCHEMBL548889 | 0.89 | NAAA (0.50) | NAAAIDH1PPARAFAAHALDH1A1 | |
| SCHEMBL292751 | 0.88 | NAAA (0.53) | NAAAIDH1PPARAFAAHALDH1A1 | |
| SCHEMBL2207671 | 0.88 | NAAA (0.53) | NAAAIDH1PPARAFAAHALDH1A1 | |
| SCHEMBL13368994 | 0.88 | NAAA (0.50) | NAAAIDH1PPARAFAAHHDAC1 | |
| SCHEMBL292752 | 0.88 | NAAA (0.53) | NAAAIDH1PPARAFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035543-A1 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2009-03-19 | — | — | WO | disclosed |