⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012396 | 0.60 | — | — | |
| SCHEMBL9930540 | 0.56 | KDM4E (0.38) | — | |
| SCHEMBL7400321 | 0.56 | — | — | |
| SCHEMBL8567643 | 0.55 | — | — | |
| SCHEMBL2115437 | 0.55 | — | — | |
| SCHEMBL31337031 | 0.53 | MAPK1 (0.33) | — | |
| SCHEMBL4315815 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL1924532 | 0.53 | HSP90AA1 (0.32) | — | |
| SCHEMBL1628118 | 0.52 | — | — | |
| SCHEMBL2120002 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3047045-B2 | — | — | 2000-05-29 | — | — | JP | claimed |
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | claimed |
| EP-0869953-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP (KR) | 1998-10-14 | — | — | EP | claimed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | claimed |
| EP-0383239-A1 | Isomeric dideoxynucleosides, their preparation and their use in medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-22 | — | — | EP | claimed |
| EP-0285884-A2 | Process to produce 2', 3'-Dideoxynucleosides | Bristol-Myers Squibb Company (US) | 1988-10-12 | — | — | EP | claimed |
| US-6110923-A | Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity | BIOCHEM PHARMA INC. (CA) | 2000-08-29 | — | — | US | disclosed |
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | disclosed |
| EP-0766683-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC (CA) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035297-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC. (CA) | 1995-12-28 | — | — | WO | disclosed |
| EP-0316017-B1 | 2',3'-Dideoxy-2'-fluoronucleosides | BRISTOL MYERS SQUIBB CO (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5218106-A | From 2'-doexy-2'-fluoronucleosides; viricides | BRISTOL-MYERS COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| US-5212294-A | Production of 2',3'-dideoxy-2',3'-didehydronucleosides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| US-4973677-A | ANTIVIRAL AGENTS, TREATMENT OF AIDS | BRISTOL-MYERS COMPANY (US) | 1990-11-27 | — | — | US | disclosed |
| US-4908440-A | 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides | BRISTOL MYERS COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| US-4904770-A | Production of 2',3'-dideoxy-2',3'-didehydronucleosides | BRISTOL-MYERS COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0340778-A2 | Prodrugs of 2',3'- Didehydro-2',3'-Dideoxynucleosides | Bristol-Myers Squibb Company (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0334368-A2 | Production of 2',3'-dideoxy-2',3'-Didehydronucleosides | Bristol-Myers Squibb Company (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0316017-A2 | 2',3'-Dideoxy-2'-fluoronucleosides | Bristol-Myers Squibb Company (US) | 1989-05-17 | — | — | EP | disclosed |
| EP-0285884-A2 | Process to produce 2', 3'-Dideoxynucleosides | Bristol-Myers Squibb Company (US) | 1988-10-12 | — | — | EP | disclosed |