SCHEMBL8567643

SCHEMBL8567643

Oc1ncnc(O)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31032243 0.81
SCHEMBL8176802 0.77 GABRA1 (0.30)
SCHEMBL31351992 0.75
SCHEMBL7821803 0.75 KMO (0.37)
SCHEMBL603330 0.75 ENPP3 (0.32)
SCHEMBL8180348 0.74 CHRM4 (0.33)
SCHEMBL31155924 0.70
SCHEMBL2115437 0.67
SCHEMBL2232292 0.67
SCHEMBL1001064 0.66 ALOX15 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117534-B A kind of security protection flame-retardant polycarbonate material and its production technology 福建盈科百创电子有限公司 2017-11-17 CN claimed
CN-106117534-A A kind of security protection flame-retardant polycarbonate material and production technology thereof 福建盈科百创电子有限公司 2016-11-16 CN claimed
CN-102250016-A Method for preparing 4,5,6-trichloropyrimidine UNIV SHAOXING 2011-11-23 CN claimed
CN-106117534-B A kind of security protection flame-retardant polycarbonate material and its production technology 福建盈科百创电子有限公司 2017-11-17 CN disclosed
CN-106117534-A A kind of security protection flame-retardant polycarbonate material and production technology thereof 福建盈科百创电子有限公司 2016-11-16 CN disclosed
CN-102250016-B Method for preparing 4,5,6-trichloropyrimidine UNIV SHAOXING 2012-11-07 CN disclosed
CN-102250016-B Method for preparing 4,5,6-trichloropyrimidine UNIV SHAOXING 2012-11-07 CN disclosed
CN-102250016-A Method for preparing 4,5,6-trichloropyrimidine UNIV SHAOXING 2011-11-23 CN disclosed
CN-102250016-A Method for preparing 4,5,6-trichloropyrimidine UNIV SHAOXING 2011-11-23 CN disclosed
EP-0826674-A1 NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-03-04 EP disclosed
WO-1993010103-A1 HERBICIDAL SULFONYLURIA DERIVATIVES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1993-05-27 WO disclosed
CN-1061969-A The sulfonyl urea derivates of weeding ICI AUSTRALIA OPERATIONS (AU) 1992-06-17 CN disclosed
WO-1992006965-A1 HERBICIDAL SULFONYLUREA DERIVATIVES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1992-04-30 WO disclosed
EP-0457581-A1 Herbicidal sulfonylurea derivatives ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1991-11-21 EP disclosed