Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | PGK2 | P07205 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663125 | 0.90 | NT5E (0.53) | ADORA3ADORA1ADORA2APGK1PGK2 | |
| SCHEMBL6657467 | 0.86 | ADORA3 (0.66) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL6657460 | 0.86 | ADORA3 (0.66) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL9413288 | 0.80 | SLC29A1 (0.57) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL7068486 | 0.80 | SLC29A1 (0.54) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL6660710 | 0.79 | SLC29A1 (0.58) | ADORA3SLC29A1ADORA1ADORA2A | |
| SCHEMBL9413321 | 0.78 | SLC29A1 (0.75) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL9413325 | 0.78 | SLC29A1 (0.75) | ADORA3P2RX3P2RX2SLC29A1ADORA1 | |
| SCHEMBL29936335 | 0.76 | ADORA3 (0.61) | ADORA3ADORA1ADORA2ANT5E | |
| SCHEMBL9413293 | 0.76 | ADORA3 (0.61) | ADORA3ADORA1ADORA2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030856-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024451-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |